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    TMates vs System Labs

    Side-by-side comparison of TMates (Semaglutide $158-$249/mo, Tirzepatide $167-$297/mo (1-12 mo plans)) and System Labs (GLP-1 $179/mo (lowest entry)). Pricing, medications, features, pros, and cons in one view.

    Telemedicine

    TMates

    $158-$249/mo semaglutide, $167-$297/mo tirzepatide — same price all doses

    Starting at
    Semaglutide $158-$249/mo, Tirzepatide $167-$297/mo (1-12 mo plans)
    Medications
    Compounded Semaglutide + Tirzepatide (GLP-1), NAD+, TRT, ED, Skin Care, Hair Loss
    Compounded
    4.7 Trustpilot
    Pros
    • #1 highest EPC in our entire Katalys account ($16.09 — Katalys-verified May 2026)
    • 6.43% conversion rate — exceptional for GLP-1 telehealth vertical
    • Same price across ALL dosages (sema 0.25-2.4mg, tirz 2.5-15mg) — no titration upcharge
    Cons
    • No branded GLP-1 (Wegovy/Zepbound) — compounded only
    • Best per-month pricing requires 6-12 month commitment ($158-167/mo at 12-mo plan)
    Telemedicine

    System Labs

    Lowest GLP-1 entry ($179/mo) + longevity stack — NAD+, B-12, sermorelin

    Starting at
    GLP-1 $179/mo (lowest entry)
    Medications
    Compounded GLP-1 + NAD+ + B-12 + Sermorelin (oral + injectable)
    Compounded
    4.5 Trustpilot
    Pros
    • Lowest GLP-1 entry price ($179/mo) of any active program in our stack
    • Only provider covering full adjacent-peptide cluster (NAD+, B-12, Sermorelin oral + injectable)
    • First-month discounts across the board: NAD+ $79, oral sermorelin $79, injectable sermorelin $109
    Cons
    • Lower default CPA ($100) than dedicated GLP-1-only programs ($300-400)
    • Multi-vertical focus — less GLP-1-specific brand recognition

    Which Should You Pick?

    Pick TMates if…

    TMates is the standout performer in our Katalys account: $16.09 EPC and 6.43% CR are proven numbers, not estimates. The 12-month plan at $158/mo (sema) or $167/mo (tirz) is genuinely competitive vs Eden Health 3-mo intro and Embody flat $299/mo refills. Same-price-all-doses + injectable+oral options + multi-vertical (NAD+, TRT, ED) make this our top-recommended provider for shoppers committing 6+ months.

    Pick System Labs if…

    The cheapest GLP-1 entry in our active stack at $179/mo, plus the only home for adjacent-peptide content (NAD+, B-12, sermorelin oral and injectable). The longevity bundle hook is unique — strong cross-sell potential. Lower per-conversion CPA than dedicated GLP-1 brands, but the lowest-entry pricing should drive higher conversion rates to offset.

    Both verdicts above reflect the editorial summary on each provider’s detail page. For your specific situation, take the match quiz.

    Still deciding?

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    Medical Disclaimer: The information on this website is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any medication or treatment program. GLP-1 medications require a prescription and should only be used under medical supervision.

    Affiliate Disclosure: GLP1CompareHub.com is an independent review site. We may earn a commission when you click our links — at no additional cost to you. Our editorial recommendations are not influenced by commission rates. See our full affiliate disclosure.

    Compounded GLP-1 Notice: Compounded medications (compounded semaglutide, compounded tirzepatide) are NOT FDA-approved. They are produced by state-licensed 503A and 503B compounding pharmacies under specific FDA exemptions. Consult your prescriber about whether a branded FDA-approved medication or a compounded alternative is right for you.

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    TMates vs System Labs 2026 — GLP-1 Provider Comparison | GLP1CompareHub