Skip to main content
    Educational content — not medical advice. Information on this page is for educational purposes only and is not a substitute for advice from a licensed physician. GLP-1 medications carry meaningful risks; speak with your doctor before starting any treatment. Compounded GLP-1 medications are not FDA-approved and clinical evidence is less robust than for FDA-approved branded products (Wegovy, Zepbound, Ozempic, Mounjaro). Read our full medical disclaimer · FDA on compounded GLP-1.

    TMates vs MEDVi 2026: Which Compounded GLP-1 Provider Wins?

    Updated May 2026 · Pricing verified directly from provider sites and Trustpilot/BBB filings

    How this page is reviewed

    Editorially reviewed by GLP1CompareHub Editorial Team. We are an independent affiliate publisher — we are not licensed medical providers and this site does not deliver medical advice. Every claim on this page is sourced to a verifiable origin (peer-reviewed study, FDA documentation, live brand-site crawl, or our Katalys partner dashboard).

    Last editorially reviewed
    Invalid Date

    Affiliate disclosure: We earn a commission when you sign up with a provider through our links — at no extra cost to you. We do not rank providers by what they pay us; we rank by patient fit. Full disclosure. Read our methodology · medical disclaimer.

    If you are considering a GLP-1 medication: consult a licensed physician familiar with your medical history. Do not start, stop, or change a prescription based on content from this site. Side effects, contraindications, and drug interactions are real and individual.

    Pick TMates if:

    You want predictable flat pricing as you titrate up to higher doses, you are willing to commit to a 12-month plan for the lowest monthly rate, you do not need bundled coaching, and you weight regulatory cleanliness — TMates has not received any FDA warning letters.

    See TMates Pricing

    Pick MEDVi if:

    You value the larger Trustpilot review base as a signal of operational maturity, you want bundled 1:1 coaching, or you prefer to evaluate the program for one month at intro pricing before committing further. MEDVi has stronger marketing and onboarding despite the FDA warning.

    See MEDVi Pricing

    Side-by-Side Comparison

    FactorTMatesMEDVi
    Compounded Semaglutide$158–$249/mo (flat across doses)$179 first / $299/mo ongoing
    Compounded Tirzepatide$167–$297/mo (flat across doses)$279–$499/mo (dose-dependent)
    503A PharmacyU.S. 503A (specific partner not publicly disclosed)Licensed U.S. partners; received FDA misbranding warning Feb 2026
    Trustpilot3.2/5 (low review volume)4.4/5 across 13K+ reviews (efficacy/billing complaints noted)
    Cancel PolicyCancel anytime, no contractCancel anytime, no contract
    Pricing ModelSame flat price across all doses (rare in industry)Tiered pricing + 1:1 coaching included + heavy marketing presence

    Where MEDVi Beats TMates

    • Larger Trustpilot review volume (13K+ reviews at 4.4/5) signaling operational maturity.
    • 1:1 health coaching included in plans — TMates is medication-only.
    • Stronger educational content and onboarding flow for first-time users.
    • First-month intro pricing ($179) lets you evaluate before committing.

    Where TMates Beats MEDVi

    • TMates has avoided the FDA misbranding-warning wave that hit MEDVi in Feb 2026 — cleaner regulatory record.
    • TMates flat-dose pricing avoids upcharge surprises; MEDVi tirzepatide can run $499/mo at higher doses.
    • TMates 12-month plan is dramatically cheaper than MEDVi ongoing ($158 vs $299 monthly for semaglutide).
    • TMates does not bundle coaching into pricing — leaner model for users who do not need or want coaching.

    Honest Take: Where TMates Falls Short

    MEDVi has 13,000+ Trustpilot reviews vs TMates lower review volume. The MEDVi reviews are mixed — many positive on coaching and ease of use, others negative on oral medication efficacy and billing — but the sheer volume gives MEDVi an operational maturity signal that TMates has not yet matched. TMates is a newer entrant and should be evaluated as such.

    Red Flag to Know About MEDVi

    February 2026 FDA Warning Letter: MEDVi was among 30+ telehealth firms cited by the FDA for marketing language that implied compounded GLP-1 products were FDA-approved. The warning addressed misbranding, not the underlying medications, but it is a real signal of regulatory friction. MEDVi has updated its marketing to comply.

    TMates · From $158/mo
    Same flat price across all doses — best for budget-conscious buyers willing to commit to 12 months.
    See Pricing
    MEDVi
    Tiered pricing + 1:1 coaching included + heavy marketing presence
    See Pricing
    glp1comparehub

    Your independent guide to comparing GLP-1 medication providers. Find the right telehealth program for your weight-loss journey.

    Independent & Unbiased

    Medical Disclaimer: The information on this website is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any medication or treatment program. GLP-1 medications require a prescription and should only be used under medical supervision.

    Affiliate Disclosure: GLP1CompareHub.com is an independent review site. We may earn a commission when you click our links — at no additional cost to you. Our editorial recommendations are not influenced by commission rates. See our full affiliate disclosure.

    Compounded GLP-1 Notice: Compounded medications (compounded semaglutide, compounded tirzepatide) are NOT FDA-approved. They are produced by state-licensed 503A and 503B compounding pharmacies under specific FDA exemptions. Consult your prescriber about whether a branded FDA-approved medication or a compounded alternative is right for you.

    © 2026 GLP1CompareHub.com. All rights reserved.

    TMates vs MEDVi 2026: Which Compounded GLP-1 Wins? | GLP1CompareHub