Medical Disclaimer: Compounded GLP-1 medications (semaglutide, tirzepatide) are not FDA-approved; they are produced by state-licensed 503A or 503B compounding pharmacies under patient-specific prescriptions. Branded products (Wegovy, Zepbound, Mounjaro, Ozempic) are FDA-approved for specific indications. Content on GLP1CompareHub is educational and is not medical advice — consult a licensed prescriber before starting, stopping, or modifying any GLP-1 medication. Full medical disclaimer.
TMates vs SkinnyRx 2026: Which Compounded GLP-1 Provider Wins?
Updated May 2026 · Pricing verified directly from provider sites and Trustpilot/BBB filings
Pick TMates if:
You are budget-conscious and willing to commit to a 12-month plan ($158/mo semaglutide, $167/mo tirzepatide flat across all doses). The savings vs SkinnyRx are largest for tirzepatide users titrating up to higher doses where flat pricing produces the biggest gap.
See TMates PricingPick SkinnyRx if:
You are a first-time GLP-1 user, you weight consumer reviews heavily, you want oral/tablet alternatives to injection, or you are risk-averse and want the strongest possible reputational signal. SkinnyRx 4.8/5 across 5,000+ reviews is the gold standard for GLP-1 telehealth credibility right now.
See SkinnyRx PricingSide-by-Side Comparison
| Factor | TMates | SkinnyRx |
|---|---|---|
| Compounded Semaglutide | $158–$249/mo (flat across doses) | $199/mo (bundles drop to ~$224 effective) |
| Compounded Tirzepatide | $167–$297/mo (flat across doses) | $299/mo (bundles drop to ~$232 effective) |
| 503A Pharmacy | U.S. 503A (specific partner not publicly disclosed) | Multiple licensed U.S. 503A pharmacies (state-board compliant) |
| Trustpilot | 3.2/5 (low review volume) | 4.8/5 across 5K+ reviews — top-tier reputation |
| Cancel Policy | Cancel anytime, no contract | Cancel anytime, no contract |
| Pricing Model | Same flat price across all doses (rare in industry) | Highest-Trustpilot reputation + injectable + oral/tablet options + bundle discounts |
Where SkinnyRx Beats TMates
- Trustpilot 4.8/5 across 5,000+ reviews — one of the strongest reputational signals in the entire GLP-1 telehealth category.
- Offers both injectable and oral/tablet semaglutide and tirzepatide formats; TMates is injectable-only.
- Multi-pharmacy 503A network gives more redundancy if one pharmacy has shipping or supply issues.
- Established track record with proven customer service quality reflected in review consistency.
Where TMates Beats SkinnyRx
- TMates 12-month plan ($158/mo) is meaningfully cheaper than SkinnyRx standard $199/mo for semaglutide.
- TMates flat-dose pricing applies across all dose tiers; SkinnyRx pricing is per-dose-tier on some plans.
- TMates tirzepatide $167/mo on 12-month plan undercuts SkinnyRx $299/mo standard substantially.
- TMates focused product line — purely compounded GLP-1, no upsell complexity.
Honest Take: Where TMates Falls Short
SkinnyRx has 5,000+ Trustpilot reviews at 4.8/5 — TMates does not have anywhere close to this. For consumers making a first-time GLP-1 decision, the SkinnyRx reputation signal is one of the strongest in the entire industry. The price difference between TMates and SkinnyRx (about $40/month at standard pricing) may be worth paying for the reputational assurance, especially for needle-averse users who benefit from the oral options. Acknowledge that TMates flat-pricing innovation does not erase a 5K-review reputation gap.
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Continue your research with these related independent reviews.